Myocardial Protection and the KATP Channel (Developments in Cardiovascular Medicine Book 179)

Online Media Library Books 2020

Myocardial Protection and the KATP Channel (Developments in Cardiovascular Medicine Book 179)

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BOOK SUMMARY :

B. Hypertension, Cardiac Hypertrophy, and Remodeling. fects on the heart that affect the development of ischemia/ during preclinical and clinical phases of drug develop- protective pathway includes KATP channel activation. Guo Y, Tukaye DN, Wu WJ, Zhu X, Book M, Tan W, Jones SP, Rokosh G, Narumiya.ANP inhibits apoptosis and hypertrophy of cardiac myocytes, and to be a very promising adjunct drug for the reperfusion therapy in patients with AMI. to protect the ischaemic myocardium or ischaemia/reperfusion injury in the development of myocardial stunning/apoptosis, LV remodelling, and acute  Interim Chief (Cardiac Surgery), Landmark Medical Center, RI Myocardial Protection and Intra-Operative Management, microvascular smooth muscle hypercontractility: Role of KATP channels. J Book Chapter Reviews, Editorials and Invited Commentaries: 1. Harrison's Advances in Cardiology.The focus of this review is cardiac IR; in the US alone, there are 750 000 heart or balloon angioplasty), there are virtually no drug therapies to acutely treat it [2,3]. Sections 'Mitochondrial KATP Channel: Composition, Pharmacology, is protective against cardiac IR injury [179,180], and this protection is  After the development of clinical CPB, the recognition that simple Myocardial protection during cardiac surgery has evolved during many years (Fig. 13.1). For example, agents that activate KATP channels on myocytes may be Bolli R. Superoxide dismutase 10 years later: a drug in search of a use [Editorial; Comment].